Anxiety is a nervousness and restless state of mind that can cause compulsive behavior or panic attacks from fears and anticipation of the unknown or misfortune. Anxiety disorders impact 40 million adults (18%) in the United States alone. Anxiety is not our default state but it does help in the critical adaptive response that helps us stay alert to threats in our environment. However, anxiety can become chronic and tremendously impact our quality of life. Unfortunately, the common way to treating anxiety is through prescription drugs which often come with unwanted side effects.
In recent years, CBD has generated great interest for its anti-anxiety effects. Below is a small sample of studies that look into CBD anxiolytic effects (most of them done in humans)
- Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report.
- Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients.
- Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug.
- Antidepressant-like and anxiolytic-like effects of cannabidiol: a chemical compound of Cannabis sativa.
- Cannabidiol regulation of emotion and emotional memory processing: relevance for treating anxiety-related and substance abuse disorders.
- Cannabidiol Does Not Dampen Responses to Emotional Stimuli in Healthy Adults.
- Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation.
- Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence.
- The anxiolytic-like effects of cannabidiol injected into the bed nucleus of the stria terminalis are mediated by 5-HT1A receptors.